📗 Libro en inglés BENIGN AND REACTIVE CONDITIONS OF LYMPH NODE AND SPLEEN

One of the main reasons that this edition was undertaken is that for some years there has been no single, up-to-date book containing extensive information on benign and reactive lymphoid conditions. Although malignant processes garner the majority of attention, it is the benign processes that have an underlying complexity that is often an illustration of the delicate interplay of many components of the active immune system. In diagnosing the pathologic specimen, a basic approach is:1. To determine if the process is benign or malignant. 2. If malignant, to characterise the origin of the malignancy. 3. To subclassify or identify the process. In some cases, the first part-the question of benign versus malignant-cannot be resolved by histomorphologic evaluation alone. The second part of the approach has become considerably easier with the advent of immunophenotypic analysis. The final issue, that of identification of the pathologic process, may be of greater or lesser importance, depending on the clinical situation. If an exact diagnosis can be made it can have several benefits.