A compreensão da citologia e histologia é fundamental para estudantes das ciências biológicas e da saúde. O caminho do aprendizado de conceitos complexos é repleto de desafios: paciência, persistênci

In Cambridge in the 1950s, several research groups funded by the Medical Research Council were producing exciting results. In the Biochemistry Department, Sanger determined the amino acid sequence of insulin, and was awarded a Nobel Prize for this in 1958. At the Cavendish Laboratory, in the MRC Unit for the Study of the Molecular Structure of Biological Systems, Watson and Crick solved the structure of DNA, and Perutz and Kendrew produced the first three-dimensional maps of protein structures haemoglobin and myoglobin for which all four were later awarded Nobel Prizes. This made it timely to create, in 1962, a new Laboratory of Molecular Biology in Cambridge by amalgamating these groups with other MRC-funded groups from London. The Laboratory has become one of the most successful in its field, and the number of Nobel Prizes awarded over the years to scientists at LMB has risen to thirteen. This book follows the development of LMB, through the people who moved into the new Laboratory and their research. It describes events and personalities that have given the Laboratory a friendly, family atmosphere, while continuing to be scientifically productive.

Un veneno es cualquier sustancia que al ser introducida o al estar en contacto con un ser vivo, le produce un efecto o una serie de trastornos que dañan su equilibrio corporal y que lo pueden conducir hasta la muerte. En esta obra se estudian las plantas, los animales y los microorganismos que poseen la capacidad de producir veneno o de obtenerlo de fuentes externas, asi como la composicion quimica de su veneno, y se muestra que son parte importante en la investigacion y cura de enfermedades, asi como en el equilibrio y conservacion de los ecosistemas.

Ao divulgarmos os benefícios da carne, concha e muco do Caracol Africano, oferecemos argumentos para estimular o seu aproveitamento racional como um patrimônio genético atualmente desprezado, chamand

"Terrific... and an oddly enjoyable read."I am very surprised this book doesnt have a review yet, and Im honored to be the first. Im a layman when it comes to this stuff; I am educated, but by no means am I a mortician, doctor, or scientist. I bought this book only for research for a novel, but Im amazed at how easy to read, how interesting, but, and most importantly, how objectively based it is.Its rare (if not impossible) to find a scientific text that is enjoyable to read while remaining completely grounded in the facts. This is a super fun book to read, and itll fill your brain with odd tidbits of information that youll be able to bring up at dinner parties for a lifetime.- A Reader Review (Amazon.com)This book is the result of many years of contact with embalmers in training and in practice. We have included in this work a crystallization of essential information without which, the embalmer must be poorly equipped to carry out the many duties incident to his calling in a manner satisfactory to his patrons and to himself. Having been thrown in contact with the many problems surrounding the education of the embalmer, the authors have gained many ideas as to just how to place the information before the embalmer so that the result will be reflected in an increased capacity for good work on the part of the individual embalmer.In prescribing information for the embalmer in this manner, we know clearly just what is to be expected from the application of the sciences herein described, and wish for the novitiate and practitioner the same enthusiasm for actual knowledge that has helped us thus far in arranging the information.In Part One, we have chronicled, from the word of historians and men of the present day, a condensed, yet complete exposition of the funeral customs relating to the care of the dead, giving our readers a better understanding of present methods by reason of an opportunity to compare them with those of the past.In Part Two, we have placed the ground work or foundation for the securing of the proper education in embalming. The work on Anatomy, which, if mastered by the student or practitioner, is by far the greatest lever in helping him to master his lifework.In Part Three, we have placed the practical application of the prin-ciples of modern embalming, tempered by the use of the sciences of pathology, bacteriology, and chemistry in our own application of the work and in its transcription to these pages. In formulating the technical part of the work, we have been greatly assisted by many authorities among whom are:Green, Howell, Thomas, Piersol, Gray, Spalteholz, Myers, Barnes, Renouard, Clarke, and those authors who have from time to time contributed articles to the current embalmers journals.We are deeply indebted to these men for the results of their work.

"Glossary of Geological and Other Scientific Terms Used in the Principles of Geology" by Charles Lyell. Published by e-artnow. e-artnow publishes a wide range of titles that encompasses every genre. From well-known classics & literary fiction and non-fiction to forgottenor yet undiscovered gemsof world literature, we issue the books that need to be read. Each e-artnow edition has been meticulously edited and formatted to boost readability for all e-readers and devices. Our goal is to produce eBooks that are user-friendly and accessible to everyone in a high-quality digital format.

Este livro foi elaborado por ex-alunos e colaboradores do Grupo NUCEL de Terapia Celular e Molecular da USP, com o objetivo de facilitar a compreensão e aplicação da técnica revolucionária de Edição

Oxygen exists in two gaseous (dioxygen and ozone) and six solid allotropic modifications. An additional allotropic modification of oxygen, the cyclooctaoxygen, was predicted to exist in 1990. The first synthesis and characterization of cyclooctaoxygen as its sodium crown complex, isolated in the form of three cytosine nucleoside hydrochloride complexes, was reported in 2016. Cyclooctaoxygen sodium was synthesized in vitro from atmospheric oxygen, or catalase effect-generated oxygen, under catalysis of cytosine nucleosides and either ninhydrin or eukaryotic low-molecular weight RNA. Thin-layer chromatographic mobility shift assays were applied on specific nucleic acids and the cyclooctaoxygen sodium complex. The cationic cyclooctaoxygen sodium complex was shown to bind to nucleic acids (RNA and DNA), to associate with single-stranded DNA and spermine phosphate, and to be essentially non-toxic to cultured mammalian cells at 0.11.0 mM concentration. It is postulated that cyclooctaoxygen is formed in most eukaryotic cells in vivo from dihydrogen peroxide in a catalase reaction catalysed by cytidine and RNA. A molecular biological model was deduced for a first epigenetic shell of eukaryotic in vivo DNA. This model incorporates an epigenetic explanation for the interactions of the essential micronutrient selenium (as selenite) with eukaryotic in vivo DNA. The sperminium hydrogen phosphate/cyclooctaoxygen sodium complex is calculated to cover the actively transcribed regions (2.6%) of bovine lymphocyte interphase genome. Cyclooctaoxygen seems to be naturally absent in hypoxia-induced highly condensed chromatin, taken as a model for eukaryotic metaphase/anaphase/early telophase mitotic chromatin. Hence, it is proposed that the cyclooctaoxygen sodium-bridged sperminium hydrogen phosphate and selenite coverage serves as an epigenetic shell of actively transcribed gene regions in eukaryotic open euchromatin DNA. It is proposed that the sperminium phosphate/cyclooctaoxygen sodium complex coverage of nucleic acids is essential to eukaryotic gene regulation and promoted proto-eukaryotic evolution. Cyclooctaoxygen sodium-bridged sperminium hydrogen selenite is calculated to serve as a marker shell component at ATG start codons in human euchromatin DNA mRNA genes, both at the translation initiation triplet and at 5-untranslated region upstream ATGs. The total herbicide glyphosate (ROUNDUP) and its metabolite (aminomethyl)phosphonic acid (AMPA) are proved to represent epigenetic poisons, since they both selectively destroy the cyclooctaoxygen sodium complex. This definition is of reason, since the destruction of cyclooctaoxygen is certainly sufficient to bring the protection shield of human euchromatin into collateral epigenetic collapse. The total herbicide glyphosate and its environmental metabolite (aminomethyl)phosphonic acid (AMPA) can be associated in vitro with catalytic detoriation of eukaryotic euchromatin genetic information. The epigenetic shell of eukaryotic euchromatin is susceptible to decay induced by catalytic epigenetic poisons threatening eukaryotic genomic heritage.

Este novo livro da coleção Maurício Tragtenberg combina diferentes artigos tendo como mote o socialismo libertário em sua práxis, ou seja, nas relações entre teoria e pratica. Nesta obra, o autor exa

In Venoms: Venomous Animals and Antivenomous Serum-therapeutics by A. Calmette, readers are taken on a comprehensive journey through the world of venomous animals and the development of antivenomous serum-therapeutics. The book delves into the composition of venoms, their effects on the human body, and the intricacies of creating effective antivenom treatments. Calmettes scientific approach is evident in his detailed descriptions and analysis of venomous creatures, making this book a valuable resource for researchers, scientists, and medical professionals in the field. Written in a clear and accessible style, the book provides a wealth of knowledge on a complex and fascinating subject. A. Calmette, a renowned scientist and researcher in the field of venomous animals and antivenomous serum-therapeutics, brings his expertise to Venoms. His extensive experience and dedication to the study of venomous creatures is reflected in the thorough research and analysis presented in the book. Calmettes passion for the subject shines through in his writing, making this book a compelling read for anyone interested in the topic. I highly recommend Venoms: Venomous Animals and Antivenomous Serum-therapeutics to readers who are curious about the fascinating world of venomous animals and the development of antivenom treatments. Calmettes authoritative voice and in-depth exploration of the subject make this book a must-read for anyone interested in biology, zoology, or medical science.

In The Principles of Stratigraphical Geology by J. E. Marr, readers are taken on a comprehensive exploration of the principles governing the study of the Earths layered rocks and their interpretation. Marrs writing style is precise and analytical, providing a detailed overview of stratigraphical geology within its scientific and historical context. The book delves into the methods of correlating rock formations, analyzing fossils, and understanding the geological timescale, making it a fundamental resource for geology students and professionals alike. Marrs incorporation of case studies and diagrams enhances the readers understanding of complex concepts. J. E. Marrs authoritative voice and clear explanations make this textbook a cornerstone in the field of stratigraphical geology. As a renowned geologist and academic, Marrs expertise shines through in this seminal work, which is a testament to his dedication to the study and research of Earths geological history. The Principles of Stratigraphical Geology comes highly recommended for anyone seeking a solid foundation in this fascinating scientific discipline.

Este libro trata de ser una introducción al campo de la Bioenergética más que una revisión extensa. Consecuentemente y en primer lugar, aunque existen opiniones discrepantes para casi todos los temas tratados, hemos basado los contenidos sobre lo que creemos que esta generalmente aceptado como ortodoxo en Bioenergetica.

Los objetivos de esta cuarta edición (correspondiente a la traducción de la quinta edición original) del Libro de Texto de Bioquímica con Aplicaciones Clínicas son: presentar una discusión clara y precisa de la bioquimica de las celulas de mamifero y, cuando este justificado, de celulas procarioticas y eucarioticas; relacionar los hechos bioquimicos a nivel celular con los procesos fisiologicos que tienen lugar en el animal entero; y citar ejemplos de procesos bioquimicos anormales en enfermedades humanas.

Los objetivos de esta cuarta edición (correspondiente a la traducción de la quinta edición original) del Libro de Texto de Bioquímica con Aplicaciones Clínicas son: presentar una discusión clara y precisa de la bioquimica de las celulas de mamifero y, cuando este justificado, de celulas procarioticas y eucarioticas; relacionar los hechos bioquimicos a nivel celular con los procesos fisiologicos que tienen lugar en el animal entero; y citar ejemplos de procesos bioquimicos anormales en enfermedades humanas.

O livro Práticas de Química Farmacêutica Medicinal: uma abordagem computacional reúne uma coletânea de oito práticas voltadas às etapas iniciais de desenvolvimento de novos fármacos com o auxílio do

Manual de Bioquímica com Correlações Clínicas trata da bioquímica celular de eucariotos, com ênfase em células e tecidos de mamíferos. As correlações clínicas são apresentadas em caixas separadas e d

El libro está dirigido sobre todo a profesionales sanitarios; las Escuelas de Enfermería lo encontrarán especialmente adecuado para sus cursos de Bioquímica y también será de utilidad para estudiantes de Medicina, e incluso medicos en ejercicio que deseen actualizar conocimientos. El diseo del libro permite estudiarlo a distintos niveles de profundidad. Las figuras añaden a menudo detalles no incluidos en el texto basico, y lo mismo ocurre con los problemas y practicas de laboratorio. Ademas, hay que tener en cuenta las secciones de complementos y aplicaciones clinicas.

Desde su primera edición la contribución de este libro a la enseñanza de la bioquímica ha sido relevante, y ha tenido una influencia decisiva en la pedagogía de la asignatura, ofreciendo una escritura excepcionalmente clara, graficas innovadoras y la cobertura de las ultimas tecnicas y avances en investigacion. Estos rasgos siguen siendo el fundamento de esta edicion, que incorpora en sus paginas los ultimos descubrimientos que han cambiado nuestra forma de pensar sobre conceptos fundamentales de la bioquimica y la salud humana.Como aspectos a destacar de esta septima edicion, cabe señalar los siguientes: la integracion del metabolismo en el contexto de la dieta y la obesidad. Nuevos capitulos sobre regulacion de genes. Ampliacion y actualizacion de las tecnicas experimentales. Mas problemas propuestos. Nuevas herramientas para visualizar y comprender las estructuras moleculares. Incorporacion de un mayor numero de Aplicaciones clinicas, totalmente nuevas. Materiales de apoyo, dirigidos tanto a los alumnos como a los profesores que basen sus cursos de bioquimica en este manual.

Desde su primera edición la contribución de este libro a la enseñanza de la bioquímica ha sido relevante, y ha tenido una influencia decisiva en la pedagogía de la asignatura, ofreciendo una escritura excepcionalmente clara, graficas innovadoras y la cobertura de las ultimas tecnicas y avances en investigacion. Estos rasgos siguen siendo el fundamento de esta edicion, que incorpora en sus paginas los ultimos descubrimientos que han cambiado nuestra forma de pensar sobre conceptos fundamentales de la bioquimica y la salud humana.Como aspectos a destacar de esta septima edicion, cabe señalar los siguientes: la integracion del metabolismo en el contexto de la dieta y la obesidad. Nuevos capitulos sobre regulacion de genes. Ampliacion y actualizacion de las tecnicas experimentales. Mas problemas propuestos. Nuevas herramientas para visualizar y comprender las estructuras moleculares. Incorporacion de un mayor numero de Aplicaciones clinicas, totalmente nuevas. Materiales de apoyo, dirigidos tanto a los alumnos como a los profesores que basen sus cursos de bioquimica en este manual.

La presente obra aborda exclusivamente los aspectos estructurales de la Bioquímica. Muchas veces estos temas suelen ser tratados de modo insuficiente o carente de sistemática. El contenido del libro trata de responder fielmente a este caracter introductorio.