Siddhartha Mukherjee

Tras los éxitos de El emperador de todos los males y El gen, Siddhartha Mukherjee se adentra en la increíble y apasionante historia de la célula. «En un relato a la vez lírico y amplio, Mukherjee nos

Magnífico, necesario y absorbente, Siddhartha Mukherjee, ganador del Premio Pulitzer por El emperador de todos los males, ha escrito una extraordinaria «biografía» del gen y una respuesta a una de la

En 2010, siete millones de personas murieron de cáncer en todo el mundo. Con esta fría estadística Siddhartha Mukherjee, médico e investigador oncológico, arranca su amplia y absorbente «biografía»,

Magnífico, necesario y absorbente, Siddhartha Mukherjee, ganador del Premio Pulitzer porEl emperador de todos los males, ha escrito una extraordinaria «biografía» del gen y una respuesta a una de la

Un libro esencial para médicos y enfermeras, y de gran utilidad para sus pacientes. Un libro de la serie TED Books que busca reflexionar sobre la naturaleza de la medicina como ciencia y sobre los principios que deben regir las relaciones entre profesionales y pacientes.El autor destaca tres principios que gobiernan la practica de la medicina y que deben ser conocidos por todos para mejorar la atencion de los pacientes y para conseguir que todos vivamos mas sanos.

Longlisted for the Baillie Gifford Prize 2023**A NEW YORK TIMES, DAILY TELEGRAPH, ECONOMIST, MAIL ON SUNDAY and GUARDIAN BOOK OF THE YEARFrom the dawn of life itself, every being that has ever lived owes its existence to the cell.''Will leave you in awe'' GuardianThe discovery of this vital form led to a transformation in medicine but also in our understanding of ourselves - not as bodies or machines but as ecosystems. It has also given us the power to treat a vast array of mortal maladies...and even to create new kinds of human altogether.Rich with stories of scientists, doctors and the patients whose lives may be saved by their work, The Song of the Cell is a stunning ode to the building blocks of life and the cutting-edge science harnessing their power for the better.

En 2010, siete millones de personas murieron de cáncer en todo el mundo. Con esta fría estadística Siddhartha Mukherjee, médico e investigador oncológico, arranca su amplia y absorbente «biografía»

¿Qué pasará cuando dominemos completamente nuestro genoma?¿Podremos crear, en nombre de la ciencia, posthumanos capaces de superar las enfermedades que nos asolan en la actualidad?Siddhartha Mukherjee, ganador del Premio Pulitzer por El emperador de todos los males, nos ofrece una detallada vision de lo que puede a llegar a convertirse la raza humana si es que, en el futuro, todavia podemos llamarla asi.Sobre El gen: Esta quiza sea la mejor historia de suspense jamas contada, una busqueda de milenios dirigida por mil exploradores, de Aristoteles a Mendel a Francis Collins, tras el enigma en el centro de cada celula. Como El emperador de todos los males, El gen es prodigiosa, torrencial y finalmente transcendente. Si te interesa en que consiste ser humano hoy y en todos los mañanas que vengan, tienes que leer este libro. Anthony Doerr, autor de La luz que no puedes verEl gen es una magnifica sintesis de la ciencia de la vida, y nos obliga a enfrentarnos con el nucleo de esa ciencia, asi como con los retos eticos y filosoficos a nuestra idea de en que consiste ser humano. Paul Berg, Premio Nobel de QuimicaMagnifico... La historia del gen se ha contado por trozos de distintas maneras, pero nunca con la perspectiva y la grandeza que Mukherjee aporta a su historia. James Gleick, New York Times Book Review

En 2010, siete millones de personas murieron de cáncer en todo el mundo. Con esta fría estadística Siddhartha Mukherjee, médico e investigador oncológico, arranca su amplia y absorbente «biografía»,

Tras los éxitos de El emperador de todos los males y El gen, SiddharthaMukherjee se adentra en la increíble y apasionante historia de la célula.«En un relato a la vez lírico y amplio,Mukherjee nos ll

Magnífico, necesario y absorbente, Siddhartha Mukherjee, ganador del Premio Pulitzer por El emperador de todos los males, ha escrito una extraordinaria «biografía» del gen y una respuesta a una de la

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjees revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writers exploration of what it means to be human.Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selveshearts, blood, brainsare built from these compartments. Hooke christened them cells.The discovery of cellsand the reframing of the human body as a cellular ecosystemannounced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimers dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumoniaall could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies.In The Song of the Cell, Mukherjee tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. He seduces you with writing so vivid, lucid, and suspenseful that complex science becomes thrilling. Told in six parts, laced with Mukherjees own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimatea masterpiece.

En un recorregut per tot el planeta que abraça uns quants segles, El gen relata la recerca per desxifrar el codi principal que ens conforma i ens defineix com a humans, que determina com som per fora i per dintre. La historia del gen comença en una retirada abadia agustina de Moravia l'any 1856, quan un monjo concep la possible existencia d'una unitat hereditaria. Enllaça amb la teoria de l'evolucio de Darwin, i topa amb els horrors de l'eugenesia nazi de la decada del 1940. El gen transforma la biologia de postguerra. Reconfigura la nostra percepcio de la sexualitat, el caracter, la capacitat d'eleccio i el lliure arbitri. Per sobre de tot, pero, aquesta historia es filla de l'enginy huma i d'uns esperits obsessius com Charles Darwin, Gregor Mendel, Francis Crick, James Watson o Rosalind Franklin, i de milers de cientifics que continuen investigant per comprendre el codi mes important de tots els codis. Aquest relat espectacular i emotiu sobre un suposit cientific que acaba cobrant vida es obra de l'autor de The Emperor of All Maladies, un dels grans llibres divulgatius que s'han escrit sobre el cancer. Entrellaçada amb la trama de El gen, pero, com un fil vermell, hi ha tambe una historia intima: la historia de la familia de Mukherjee i el seu patro recurrent de trastorns mentals, que ens recorda que la genetica te una importancia transcendental en la vida quotidiana de tothom. Aquestes questions esdevenen encara mes vibrants i peremptories avui dia, en que estem aprenent a llegir i a escriure el genoma huma, amb totes les possibilitats que comporta de modificar el desti i la identitat dels nostres infants. El gen, amb una noble ambicio i una honestedat incorruptible, ens proporciona un relat insuperable sobre la unitat fonamental de l'herencia i un panorama tant del passat com del futur de la humanitat.Que n'han dit:Excepcional. Segurament un dels llibres de ciencia mes captivadors, potents i elegants que es pugui llegir.The Times Segurament es tracta de la historia de detectius mes important de tots els temps: una recerca de milers d'anys feta per una infinitat d'exploradors, des d'Aristotil a Collins passant per Mendel, per mirar de descobrirels interrogants que hi ha al cor de totes les cel·lules. El gen es un llibre prodigios, de gran envergadura, absolutament cabdal. Tothom qui estigui interessat a saber que significa -i que significara en el futur- ser huma, necessita llegir aquest llibre.Anthony Doerr, Premi Pulitzer 2015

A fast‑paced mystery where a detective races against time to solve a disappearance linked to a dark past.

NEW YORK TIMES NUMBER ONE BESTSELLER The Gene is the story of one of the most powerful and dangerous ideas in our history from the author of The Emperor of All Maladies The story begins in an Augustinian abbey in 1856 and takes the reader from Darwin s groundbreaking theory of evolution to the horrors of Nazi eugenics to present day and beyond as we learn to read and write the human genome that unleashes the potential to change the fates and identities of our children Majestic in its scope and ambition The Gene provides us with a definitive account of the epic history of the quest to decipher the master code that makes and defines humans and paints a fascinating vision of both humanity s past and future For fans of Sapiens by Yuval Noah Harari A Brief History of Time by Stephen Hawking and Being Mortal by Atul Gwande Siddhartha Mukherjee is the perfect person to guide us through the past present and future of genome science Bill Gates A thrilling and comprehensive account of what seems certain to be the most radical controversial and to borrow from the subtitle intimate science of our time Read this book and steel yourself for what comes next Sunday Times

Winner of the Guardian First Book Award 2011 Winner of the Pulitzer Prize for Non-fiction 2011 Shortlisted for the Duff Cooper Prize 2011 Shortlisted for the Wellcome Trust Book Prize In The Emperor of All Maladies, Siddhartha Mukherjee, doctor, researcher and award-winning science writer, examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience and perseverance, but also of hubris, arrogance and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out 'war against cancer'. Mukherjee recounts centuries of discoveries, setbacks, victories and deaths, told through the eyes of predecessors and peers, training their wits against an infinitely resourceful adversary. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteeth-century recipient of primitive radiation and chemotherapy and Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through toxic, bruising, and draining regimes to survive and to increase the store of human knowledge. Riveting and magesterial, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments and a brilliant new perspective on the way doctors, scientists, philosophers and lay people have observed and understood the human body for millennia.

¿En qué punto nos encontramos en nuestra batalla contra el cáncer y cómo hemos llegado hasta aquí? ¿De qué forma ha ido cambiando nuestra imagen de esta enfermedad y cómo ha influido esa evolución en la propia trayectoria del mal? ¿Estamos ganando o perdiendo la guerra contra el cancer? Esta magistral obra, ganadora del Premio Pulitzer, responde a estas preguntas partiendo de una reciente consideracion: el cancer no es solo un fenomeno medico. Se trata tambien de un fenomeno social que ocupa un complejo espacio cultural y politico. Su historia no puede contarse exclusivamente como un ensayo cientifico sino tambien como un relato profundamente humano. Este guarda testimonios de lucha y optimismo, de descubrimientos revolucionarios y terribles decepciones, de heroes y victimas, y de la incansable busqueda de una cura. Siddartha Mukherjee ha realizado una labor epica en la que aborda el cancer con la precision de un biologo celular, la riqueza en detalles de un novelista, el registro de un historiador y la pasion de un biografo. Desde Atosa, la reina de Persia, que dio instrucciones a un esclavo para que le extirpara un pecho, hasta Carla, una de sus pacientes, Siddhartha Mukherjee aborda en este fascinante libro mas de 5.000 años de descubrimientos, obstaculos, victorias y muerte.

The Emperor of All Maladies is a magnificent, profoundly humane biography of cancerfrom its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologists precision, a historians perspective, and a biographers passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived withand perished fromfor more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out war against cancer. The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjees own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to surviveand to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.