Ebooks de ciencias, página 27 de 725

Frontiers in Clinical Drug Research - Anti-Cancer Agents - Volume 1 should prove to be a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field. The chapters in this volume have been written by leading experts from the field.The contents of this book include new approaches to cancer therapy, treatment of metastatic non-small cell lung cancer with epidermal growth factor receptor-tyrosine kinase inhibitors, targeting key signaling pathways in pediatric brain tumors, current status of cladribine in lymphoid and myeloid malignancies, natural anti-cancer products and the mechanisms of telomere and telomerase regulation in hematologic malignancies. The eBook series is essential to all scientists involved in clinical drug research who wish to keep abreast of rapid and important developments in the field. The readers will find these reviews valuable and will certainly trigger further research in the pharmaceutical development of anti-cancer agents.

Recent advances in science and technology such as online monitoring techniques, coupling of various processing methods, surface characterization and measurement techniques have greatly promoted the development of ultraprecise machining technology. This precision now falls into the micrometer and nanometer range - hence the name micro & nanomachining technology (MNT). Machining is a complex phenomenon associated with a variety of different mechanical, physical, and chemical processes.Common principles defining control mechanisms such as O Jamie de geometry, Newton mechanics, Macroscopic Thermodynamics and Electromagnetics are not applicable to phenomena occurring at the nanometer scale whereas quantum effects, wave characteristics and the microscopic fluctuation become the dominant factors. A remarkable enhancement in computational capability through advanced computer hardware and high performance computation techniques (parallel computation) has enabled researchers to employ large scale parallel numerical simulations to investigate micro & nanomachining technologies and gain insights into related processes. Micro and Nanomachining Technology - Size, Model and Complex Mechanism introduces readers to the basics of micro & nanomachining (MNT) technology and covers some of the above techniques including molecular dynamics and finite element simulations, as well as complexity property and multiscale MNT methods.This book meets the growing need of Masters students or Ph.D. students studying nanotechnology, mechanical engineering or materials engineering, allowing them to understand the design and process issues associated with precision machine tools and the fabrication of precision components.

This brief book is dedicated to the quantitative analyses and systematic discussion of spatial biodiversity and biogeographic patterns in the Asia?pacific region comprised of China, India and adjacent countries. The book is split into two sections. The first section presents readers with detailed statistical methods to conduct spatial macro?biodiversity and biogeography analyses. Step-by-step instructions on how to perform these statistical methods by using the statistical program R are also provided. In the second part, different quantitative case studies are presented covering several topics, including phylogenetics, spatial statistics, multivariate statistics and ecological genomics. Each case study concludes with a detailed interpretation of the quantitative results and how these results are relevant to local and regional ecological processes. This reference is suitable for academics interested in biostatistics biodiversity and ecological studies specific to the Asia Pacific region and China.

Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. The second volume of this series features reviews on several key topics in this field including cardiac regeneration strategies, induced pluripotent stem cell therapeutics, stem cell therapy for peripheral nerve and cutaneous injuries, dental tissue regeneration, the potential of stem cell differentiation into ovarian cells and much more.

Frontiers in Clinical Drug Research Anti infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the eBook series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology.The second volume of this series features reviews that cover a variety of topics including: -Identification of nosocomial pathogens and antimicrobials using phenotypic techniques-Topical antimicrobials-Anti-infective drug safety-Antimicrobial resistance and much more.

Mycology: Current and Future Developments is a book series that brings together latest contributions to research on the biology, genetics, and industrial use of fungi. Each book chapter is written by experts from around the world. The book series would be of interest to mycologists and allied researchers seeking to gain new knowledge perspectives about fungi. This volume of the book series focuses chiefly on advances in biofuel production. Topics covered in this volume include an overview of biofuel production, the use of lignocelluloses in fungal biofuel production, fungal metabolic engineering, biomass pretreatment for biofuel refineries, and more. The volume also contains chapters about research on other fungi such as S. Cerevisiae. The reviews presented in this volume serve as a useful reference for researchers and readers interested in learning about new developments in biofuel production at a time when the need for alternative energy sources is ever increasing.

The need for the development of biomaterials as scaffold for tissue regeneration is driven by the increasing demands for materials that mimic functions of extracellular matrices of body tissues. Unfolding the Biopolymer Landscape provides a unique account of biopolymeric interventions inherent to biotechnological applications, soft tissue engineering, ophthalmic drug delivery, biotextiles, environmentally responsive systems, neurotherapeutics, and emulsions-based formulations for food and pharmaceutical applications. Chapters in this volume also cover biomedical applications and implications of cationic polymers, collagen-based substrates, multifunctional polymers, shape memory biopolymers, hybrid semisynthetic biomaterials, microbial exopolysaccharides, biomaterials mimicking the extracellular microenvironment, derivatized polysaccharides, and metallic biomaterials. Each chapter is distinctly written by experts in the respective fields and emphasis is given on the mechanistic profile of the performance of biopolymers and biomedical applications. This book provides both basic and advanced biopolymer information for scientific experts and early career researchers in the field of drug delivery, tissue engineering, nanomedicine, food technology, peptide science, biomaterial design, and nutrition.

Plants have been widely used to treat diseases, owing to the presence of bioactive compounds (phytochemicals) which play important roles in health promotion and disease prevention. In recent years, advances in chemical extraction techniques, lifestyle and dietary choices for human health have increased the interest in the consumption and study of fruits, vegetables, and foods enriched with bioactive compounds and nutraceuticals. Thousands of dietary phytochemicals, such as flavonoids, phenolic acids, glucosinolates, terpenes and alkaloids, have been identified and categorized further according to a diverse array of biochemical properties. Many of these phytochemicals have been hypothesized to reduce the risk of several pathological conditions which include life threatening diseases such as heart disease and cancer, to name a few.Natural Bioactive Compounds from Fruits and Vegetables as Health Promoters is a 2 book set which presents a summary of different classes of phytochemicals commonly found in common edible food sources. Each chapter details the general chemical structures of compounds, naturally present in specific fruits, vegetables and grains, their biological importance and mechanisms of action.The book set is an essential handbook for anyone interested in the natural product chemistry of these common crops.Part 1 of this set covers details about different fruits (banana, citrus fruits, pears, etc.). Part 2 covers legumes, nuts, seeds and cereals.

Nanotechnology is a diverse science that has brought about new applications in fields such as colloidal science, device physics and supra molecular chemistry. This volume gives an overview of the development of nanomaterial applications in energy and power generation, medicine and healthcare, water purification, biotechnology, electronics, sporting goods, environmental issues, military defense, and textile/fabric industries. The text also explains the fundamentals of polymer nanocomposites and their industrial applications. Other chapters cover semiconductor applications of nanomaterials, nanomaterial synthesis, characterization of nanocomposites and uses of nanofillers. Readers will also find notes on the DFT study of II-VI semiconducting nano-clusters.This volume is intended to be an introductory reference for students and researchers undertaking advanced courses in materials science and engineering, giving readers a glimpse into the fascinating world of nanotechnology.

Maintaining ideal fish health and production, both of farmed and wild fish populations, requires continuous infrastructural and process upgrades to avoid significant losses as well as to facilitate seafood safety. Aquaculture is multidisciplinary in nature, combining knowledge from biology, veterinary medicine and food technology.Practical Notions on Fish Health and Production brings an integrated approach concerning practical aspects of ichthyology, fish health and aquaculture systems. The textbook will give readers a better understanding of issues related to the management of fish health and production, seafood processing, security, quality and safety.The book is organized in three sections which cover 1) general aspects of fish biology and development, 2) fish diseases and veterinary medicine, and 3) aquaculture and marine food supply chain management. Practical Notions on Fish Health and Production is an essential text for students, food industry professionals and novice fish farmers undertaking courses or training programs in veterinary medicine, aquaculture, and marine food processing systems.

In life, we often face unavoidable complexities in terms of our ability to understand or influence outcomes. Some questions which arise due to these complexities are: Why cant the future be made certain? Why do the some people or events always end up at the center of controversy? Why do only a select few get ahead of their peers? Each question pertains to three central elements of complexities and these elements are: uncertainty, inequality and unfairness.Simplifying Complexity explains the scientific study of complex cognitive networks, as well as the methods scientists use to parse difficult problems into manageable pieces. Readers are introduced to scientific methodology and thought processes, followed by a discourse on perspectives on the three elements of complexity through concepts such as normal and non-normal statistics, scaling and complexity management. Simplifying Complexity combines basic cognitive science and scientific philosophy for both advanced students (in the fields of sociology, cognitive science, complex networks and change management) and for general readers looking for a more scientific guide to understanding and managing the nature of change in a complex world.

Genome science or genomics is essential to advancing knowledge in the fields of biology and medicine. Specifically, researchers learn about the molecular biology behind genetic expression in living organisms and related methods of treating human genetic diseases (including gene therapy). Advances in Genome Science is an e-book series which provides a multi-disciplinary view of some of the latest developments in genome research, allowing readers to capture the essence and diversity of genomics in contemporary science. The fourth volume of this ebook series features a selection of articles covering the genetic mechanisms in the development of specific plants (orchids, thale cress), Prader-Willi Syndrome, enzyme genetics (tyrosine kinase inhibitors and fungal laccases) and much more.

This book explores cutting-edge biocarbon polymer composites. The book brings together nine edited chapters that explore the development, properties, and applications of these eco-friendly materials, highlighting their potential to transform industries and reduce the environmental impact of traditional polymers. Spanning a range of critical topics, this book begins with an introduction to biocarbon and polymer materials, providing a solid foundation. It then progresses into the latest research on biocarbon sources, processing techniques, and characterization methods. Subsequent chapters cover the mechanical, thermal, and electrical properties of biocarbon polymer composites, along with their applications in diverse industries such as automotive, construction, and packaging. Contributors highlight real-world case studies and examples to showcase the practical relevance of these materials. Readers will gain a comprehensive understanding of the science and technology behind biocarbon polymer composites, enabling them to make informed decisions in materials selection and development. In an era of increasing environmental consciousness, this book emphasizes the eco-friendly nature of biocarbon composites, offering sustainable alternatives to traditional plastics. Additionally, this book bridges the information gaps between different disciplines and it is intended for a wide range of readers, from materials scientists and engineers to environmentalists and industry policymakers. Readership: Researchers and scientists in materials science and engineering; Professionals in industries seeking sustainable alternatives to traditional plastics; Environmentalists and policymakers interested in promoting eco-friendly materials; Academics and students studying materials science, polymer chemistry, and sustainable technologies; Innovators and entrepreneurs looking to capitalize on emerging materials trends

Where Did They Come From? The Origins of South American Fauna offers a fascinating journey into the origins of South American flora and fauna. Exploring life on the continent before and after the breakup of Gondwana, it delves into how creatures arrived in South America, be it through drifting across oceans or traversing land bridges. From birds and reptiles to mammals and fish, this book provides a comprehensive compendium of biological diversity, discussing their origins and evolutionary paths. Readers will gain insights into the mechanisms of animal dispersal, evolution, and the impact of the Great Biotic Interchange. The book also lists references for further exploration of the subject. The book is structured into five parts: Building South America: Covers tectonic movements, climate changes, and breaching isolation. Shaping South America: Explores the landforms and diverse biomes across the continent. Vertebrates within South America: Discusses unique amphibians, reptiles, fish, mammals, and birds that evolved on the continent. Vertebrates immigrating to South America: Examines exotic reptiles, birds, and mammals that found their way to the continent. The author also lists the families of almost all genera of South American animals, while giving knowledge of their origins. Recent Arrivals - the Great Biotic Interchange: Explores the significant interchange of various species that occurred later. Ideal for students, biologists, and anyone curious about the natural world, this book is a captivating read that uncovers the incredible history of South American fauna and its evolutionary tapestry.

Modern Wood HarvestingExpertise from professional practice for use in professional practiceLearn the necessary basic theory, and using case studies and practical examples become familiar with modern wood harvesting and forestry techniques. The following areas in particular are discussed in detail: Fundamental principles and technical terms Planning and organisation of wood harvesting tasks The most important wood harvesting procedures State-of-the-art forestry techniques Eco-friendly use of technology Hauling and debarking wood Wood storage and transport, logistics Logging models Occupational health and safety

Dog DiseasesWhich organs are affected by which diseases when your dog is sick? What are the causes of the disease? Which symptoms are indicative of which diseases? Which diagnostic and therapeutic measures can you expect from your vet? What are the prospects for a recovery? And how can you guard against a particular disease? This reference book provides the most important background information on these questions that dog owners may wish to discuss with their vet.An informative read both before and after every visit to the vet!

Anthropogenic changes in the environment, caused by 250 years of economic growth and utilization of fuel and mineral resources, have considerably impacted the natural environment. The resulting physical and chemical alterations to the Earths sphere and our adaptive responses in the biosphere are detailed in this reference book. Readers will learn about concepts relevant to Earths history, the evolution of life, economy, ecology, environmental history, biology, and medicine and how these concepts can be linked to environmental change. The scope of this interdisciplinary work entails to convey the true degree of responsibility for the universal consequences of ecosystem degradation resulting from industrial processing, human consumption and the transformation of natural sites due to industrialization and urbanization.Topics covered in the book include:-ecosystem transformations by natural and anthropogenic forces-the Anthropocene epoch-a short history of industrialization-environmental sites and the impact of socio-economic influences -the current environmental crisis,This textbook is intended for graduate students in economics, civil engineering, architecture, agronomics, forestry, technical and mining sciences, political sciences, business studies and humanities. General readers who wish to understand the basic philosophy behind environmental studies and their relation to human activity can also benefit from this book.

Tropical Diseases: An Overview of Major Diseases Occurring in the Americas offers an overview of neglected tropical diseases found in the Americas. Information in the book addresses the understanding of challenges faced in controlling these diseases and brings new insight on many important aspects of these diseases. Chapters of this volume explore many related topics, including epidemiological data, immune response and pathogenesis, and the current methods for diagnosis and treatment, thus providing a useful resource for readers (undergraduate, graduate and Ph.D. students as well as biologists and medical researchers). Key features of this book include:clear and objective topic-by-topic information on tropical diseases in the American region with additional information about diseases in other regionsuseful knowledge for research projects and clinical practice written by experienced health professionalscoverage of several diseases such as cutaneous and visceral leishmaniasis (Kala-azar), Chagas disease, sleeping sickness, schistosomiasis, dengue fever, bacterial infections, fungal systemic infection and tuberculosis.information on key strategies for disease control including improved diagnostics, in silico drug development and vaccine control

Frontiers in Nanomedicine offers an up-to-date understanding of nanomaterials to readers having clinical or biomolecular research interests. Scientists, both aspiring and experienced, will find, in each volume, a comprehensive overview of current molecular strategies for using nanoscale materials in medicine. Nanomedicine and Neurosciences: Advantages, Limitations and Safety Aspects presents different aspects of nanomedicine applied to neuroscience for the diagnosis of disease and the role of nanoparticles in targeted drug delivery systems for neurodegenerative disorders. Topics covered in this volume cover the physiology of neurodegeneration, targeted therapies for Alzheimers disease and Parkinsons disease, blood brain barrier drug delivery systems, in vivo studies of drug nanoconjugates, nanomedicine safety, and more.

Frontiers in Clinical Drug Research Anti infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the eBook series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology.The fourth volume of this series features reviews that cover a variety of topics including: -Strategies to prolong antibiotic life-Catalytic antibodies for targeting rabies and influenza viruses-Antiviral therapies for arenaviruses-The role of steroids in viral infections-Monoclonal antibody manufacturing processes-Prevention and eradication of biofilms in medical devices