Ebooks de ciencias, página 6 de 685

Frontiers in Clinical Drug Research Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The sixth volume of this series features these interesting reviews: - Direct-acting antiviral drugs for treatment of Hepatitis C virus infection - Plant lattices as anti-infective compounds - Antimicrobial materials and devices for biomedical applications - Recent advances in the treatment of toxoplasmosis - Antimicrobial immunoglobulin prophylaxis and therapy - Targeting Magnesium Homeostasis as Potential Anti-Infective Strategy Against Mycobacteria

Enzyme inhibitors play a pivotal role in pharmaceutical and nutraceutical industries. The primary understanding of the action of inhibitors helps pharmacologists during the design process for developing new therapeutic drugs. Most drugs treat various chronic and life threatening diseases owing to their specificity and the potency of enzymes which they can inhibit. Enzyme inhibitors are used to screen various levels of diseases which propel the growth of inhibitors. The potential for enzyme inhibitors in the therapeutics market is very high as the biochemical properties and classes of enzyme inhibiting products are readily available. The other broad aspect of enzyme inhibition is their application in analytical sensors. These sensors assist in monitoring various environmental factors. Understanding the mechanism of inhibition and regeneration of enzymes is a general problem of great importance for many biochemists and biotechnologists especially when using immobilized enzymes. This reference compiles applied information about enzyme inhibitors used in medicine and environmental monitoring applications. Chapters presented in this volume cover special topics including biosensors, crop improvements in agriculture, biofuel production, pesticide and heavy metal detection, and drug therapy for human diseases such as breast cancer, neurological diseases and viral infections. The collection of topics in this volume makes it an informative resource for readers at all academic levels on the applications of enzyme inhibitors in medicine and environmental sciences.

Frontiers in Computational Chemistry presents contemporary research on molecular modeling techniques used in drug discovery and the drug development process: computer aided molecular design, drug discovery and development, lead generation, lead optimization, database management, computer and molecular graphics, and the development of new computational methods or efficient algorithms for the simulation of chemical phenomena including analyses of biological activity. The fifth volume of this series features these six chapters: - Recent Advances and Role of Computational Chemistry in Drug Designing and Development on Viral Diseases- Molecular Modeling Applied to Design of Cysteine Protease Inhibitors A Powerful Tool for the Identification of Hit Compounds Against Neglected Tropical Diseases- Application of Systems Biology Methods in Understanding the Molecular Mechanism of Signalling Pathways in the Eukaryotic System- Implementation of the Molecular Electrostatic Potential over GPUs: Large Systems as Main Target- Molecular Electron Density Theory: A New Theoretical Outlook on Organic Chemistry- Frontier Molecular Orbital Approach to the Cycloaddition Reactions

Terpenoids are commercially important chemicals found in essential oils and other natural plant sources. They are used in solving issues that affect agricultural production, making them a key component of sustainable agronomy. Terpenoids: Recent Advances in Extraction, Biochemistry and Biotechnology provides information about the varied use of terpenoids in the control of pests, microbial diseases, ticks, and weeds. Chapters have prioritized terpenoids produced by plants, endophytic fungi, propolis, and geopropolis. The book also provides focused information about the functions of terpenoids in plants, as well as their biosynthetic pathways of production. The reference provides readers with a broad and diverse picture of the applications of terpenoids in plant safety, and creates an awareness of the possibilities for innovative biotechnological approaches for their extraction that make all the difference to agricultural production. Professionals and scholars involved in chemical technology, biotechnology and agriculture will benefit from the information provided in the book. It also serves as a comprehensive update for general readers interested in terpenoids and their current impact on the agricultural industry.

The advent of large-scale production and clinical trials of drugs developed through diverse production routes - involving viruses, microbes, plants, and animals - has increased the demand for an expanded capacity for pharmaceutical manufacturing. The production and purification of expressed proteins accounts for the bulk of the manufacturing costs for new therapeutics. Several pharmaceutical proteins have been synthesized by exploiting plant genetics allowing producers to override conventional approaches used to manufacture pharmaceuticals. The process of inserting a gene into a host organism for the purpose of harvesting a bioactive molecule for therapeutic use is known as molecular pharming. Frontiers in Molecular Pharming covers an array of topics relevant to understanding the structure, function, regulation, and mechanisms of action, biochemical significance, and usage of proteins and peptides as biomarkers, therapeutics, and vaccines for animals and humans. The contributions aim to highlight current progress in three areas, including system biology (in vivo characterization of proteins and peptides), molecular pharming for animals and molecular pharming for humans. The book gives special attention to computational biology tools, production platforms and fields (such as immunoinformatics) and applications of molecular pharming (such as veterinary therapeutics). A balance of theoretical concepts and practical applications is provided through 13 chapters. Frontiers in Molecular Pharming is an invaluable resource for students and researchers of biochemistry, molecular biology, and biotechnology. The book also serves as a springboard for understanding the process of how discoveries in protein and peptide research and its applications are coming to fruition.

Edible algae, including seaweeds, are a source of functional food, dietary supplements, metabolites and bioactive compounds. Algal-based functional foods have potential health benefits, and their commercial value depends on their applications in the food and nutraceutical industries. This book covers several aspects of algal based functional foods. It informs the reader about algal cultivation techniques, environmental impact, habitat, nutraceutical potential, extraction of bioactive metabolites, functional-food composition, bio-prospection, culture-induced nutraceutical compounds, algae-based bio-packaging, algal-biorefinery, toxicity, trends and future prospects. The editors present the topics in a research-oriented format while citing scholarly references. This book is a comprehensive resource for anyone interested in the nutritional benefits and industrial utilization of algae as a sustainable food source.

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. This volume presents the following chapters:- On Water And In Water Strategies for Heterocyclic Transformations- Ionic Liquid Based Polyoxometalates as Functionalized Organic-Inorganic Hybrid Materials for Catalytic Organic Reactions- Recent Advances in the Synthesis and Bio-Applications of some Oxygen and Sulphur Containing Seven Membered Heterocyclic Compounds- Application of Nitriles on the Synthesis of 5-Membered Azaheterocycles: An Update from 2014 To 2020- The Role of Carbon-Based Solid Acid Catalysts in Organic Synthesis

Sustainable Utilization of Fungi in Agriculture and Industry covers current knowledge about different fungal microorganisms, including economically important filamentous fungi and yeasts. 22 chapters summarize information about scientific investigations and the application of fungi in the production of industrial enzymes, organic acids (citric acid, lactic acid, etc.), biofuel (ethanol and hydrogen) and bioactive compounds for sustainable processes in agriculture, bioremediation, and the industrial production of pharmaceuticals. Each chapter gives an updated and detailed account on fungal microbes and their sustainable utilization in agriculture, white biotechnology, and other valuable industrial applications. Contributions are written by experts in mycology and industrial biotechnology, presenting a broad perspective of the field in a simple, yet engaging style. Sustainable Utilization of Fungi in Agriculture and Industry is an informative reference for general readers, trainees, interested in sustainability measures in agriculture and industry. The book also serves as a resource for scholars, students and teachers involved in botany, microbiology, biotechnology and life sciences courses.

Myconanotechnology is the interface between mycology andnanotechnology. In other words, myconanotechnology represents the greensynthesis of nanoparticles using fungi. The field is recently gaining attentiondue to the simple, resource efficient, and ecofriendly nature of fungal biotechnology.Therefore, Myconanotechnology is at the core of cost-effective and sustainablesolutions for many industrial processes. This volume provides readers at all academic levels with a broadbackground on some of the fastest developing areas in myconanotechnology. It isorganised into two sections, A and B. Section A updates readers on severalcutting-edge aspects of the synthesis and characterization of nanoparticlesthrough the use of fungi. Section B describes applications of myconanotechnologyincluding: the management of bacterial and fungal diseases, pest control, amongother applications in medicine and agriculture. The breadth of topics covered inthe contents make this volume an informative resource on the field. Contributionsare written by experts in industrial biotechnology, and include extensivereferences to published studies. This book is a timely reference for researchers, teachers and students,and all readers who are interested in new developments in industrial mycologyand nanotechnology.

Frontiers in Computational Chemistry presents contemporary research on molecular modeling techniques used in drug discovery and the drug development process: computer aided molecular design, drug discovery and development, lead generation, lead optimization, database management, computer and molecular graphics, and the development of new computational methods or efficient algorithms for the simulation of chemical phenomena including analyses of biological activity. The sixth volume of this series features these six different perspectives on the application of computational chemistry in rational drug design: 1. Computer-aided molecular design in computational chemistry 2. The role of ensemble conformational sampling using molecular docking & dynamics in drug discovery 3. Molecular dynamics applied to discover antiviral agents 4. Pharmacophore modeling approach in drug discovery against the tropical infectious disease malaria 5. Advances in computational network pharmacology for Traditional Chinese Medicine (TCM) research 6. Progress in electronic-structure based computational methods: from small molecules to large molecular systems of biological significance

Se empieza con una colección de ejercicios prácticos, se añaden algunas fórmulas clave, se introducen problemas tomados de situaciones reales y se salpica con algunos párrafos de explicación: si uno divaga sobre un tema de esta manera, no teniendo el buen sentido de saber cuando ha de pararse, uno acaba escribiendo un OMNILIBRO. Esto es lo que ha ocurrido en este libro.

Drawing together the evidence of archaeology, palaeoecology, climate history and the historical record, this first environmental history of Scotland explores the interaction of human populations with the land, waters, forests and wildlife. This volume spans 450 years that saw profound transformation in Scotlands environment. It begins in the fifteenth century, when the Golden Age of the early 1200s was but a fading folk memory in a land gripped by the gathering grimness of a little ice age. Colder, wetter, stormier weather became the new normal, interspersed with brief episodes of warmer but still moist conditions, all of which brought huge challenges to a society on the knife-edge of subsistence. Viewing the religious and political upheavals of the sixteenth and seventeenth centuries against the cycles of disease and dearth that were ever-present into the later 1700s, the book explores the slow adoption and application of the ideas of Improvement and the radical disruption of Scotlands environment that ensued. Reformation, revolution and rebellion were the background noise to efforts to subsist and succeed through a hostile age, in which Scotlands environment was an adversary to be tamed, mastered and made polite. As the last, bitter decades of the little ice age were ground out in foreign wars, forced clearances and potato famines, Scotland prepared itself to embrace the Industrial Age.

The historical horse is at once material and abstract, as is the notion of the border. Borders and frontiers are not only markers delineating geographical spaces but also mental constructs: there are borders between order and disorder, between what is permitted and what is prohibited. Boundaries and liminal spaces also exist in the material, economic, political, moral, legal and religious spheres. In this volume, the contributing authors explore the theme of the liminality of the horse in all of these historical arenas, asking how does one reconcile the very different roles played by the horse in human history?

Las plantas de proceso y energía requieren, para su funcionamiento seguro y eficiente, complejos sistemas de control. Estos, a su vez, se apoyan en multitud de instrumentos, así como en redes de comunicaciones digitales industriales.Por todo ello, en los proyectos de ingenieria de tales plantas, la parte correspondiente a los sistemas de control e instrumentacion ocupa un lugar esencial. Este libro, escrito por profesionales especializados en diversos aspectos de estas tecnologias, sirve de guia para el desarrollo de tales proyectos. Su enfoque eminentemente practico no descuida los fundamentos basicos teoricos delas disciplinas involucradas. El contenido del libro puede ser util tanto a los profesionales con experiencia en estas materias como para aquellos lectoresque se estan iniciando en este apasionante campo de la ingenieria. La ediciondigital del libro ha facilitado el complementarlo con utilidades y programas de calculo de diversas tareas en los proyectos, lo que enriquece su valor comoherramienta para las labores de ingenieria y le otorga una nueva dimension practica.INDICE: INGENIERIA DE PROYECTOS DE INSTRUMENTACION.Conceptos generales. Conceptos basicos de plantas de proceso. Sistemas de control. Sistemas de transportes de señales. Proteccon de instrumentos. Norma aplicable a los proyectos. Recursos informaticos. INGENIERIA B?SICA. Anexos. ACTIVIDADES DE 1ª FASE DE PROYECTO. Conceptos generales. Otras actividades. Software complementario y corporativo. Sistemas auxiliares. Anexos. GENERALIDADES DE 2º FASE DE PROYECTO. Conceptos Generales. Documentacion de montaje de instrumentos. Actividades de obra.GESTIEN DE PROYECTOS . UTILIDADES

En este libro se exponen, con claridad, los fundamentos científicos de la Química Orgánica, las propiedades de los compuestos orgánicos y los métodos de síntesis, para desembocar en sus aplicaciones tecnologicas y en los procesos industriales de fabricacion. Se exponen los principios cientificos vigentes, en su relacion con las aplicaciones tecnicas y como fuerza impulsora del extraordinario desarrollo de la Industria Quimica y de la Biotecnologia.El libro esta escrito para estudiantes universitarios y puede servir para un curso de introduccion y para un 2º curso de ampliacion; para ello, esta impreso en dos tipos de letra, siendo recomendable que, en la primera lectura, se prescinda de la tipografia mas pequeña. Ademas, contiene muchas tablas y cuadros para que sirva tambien como libro de consulta y conserve su validez despues de superados los estudios oficiales.

Esta Introducción a la Física del estado sólido, es un texto para alumnos avanzados de Ciencias e Ingeniería que han de iniciarse en el tema. Es el texto más citado dentro de su campo. En él se estudian las propiedades que resultan de la distribucion de los electrones en los metales, semiconductores y aislantes. Tambien se nos dice como comprender las excitaciones elementales e imperfecciones de los solidos, cuya potencia y utilidad estan firmemente establecidos en la actualidad.

Química Orgânica: terpenos e rotas de síntese. Terpenos: utilidade, classificação, biossíntese, nomes, funções, reações. Rotas de síntese: síntese do ácido acetilsalicílico.

Este libro es una introducción al tratamiento de aguas residuales industriales y domésticas, dirigida tanto a estudiantes como a licenciados en Ingeniería, Biología, Química, etc. interesados en este

Advanced Catalysts Based on Metal-organic Frameworks is a comprehensive introduction to advanced catalysts based on MOFs. It covers basic information about MOF catalysts with industrial and environmental applications. It updates readers on current applications and strategies to apply MOF-based catalysts in industrial processes geared for sustainability initiatives such as renewable energy, pollution control and combating carbon emission. Key Features- 13 structured, easy to read chapters that comprehensively cover MOF catalysts- An introduction to basic information about MOF catalysts - In-depth coverage of advanced applications of MOF catalysts- Explanation of MOF modifications and applications of derivative compounds- In-depth coverage of MOF catalysts used for electrocatalysis and photocatalysis- Detailed explanation of environmental-friendly and sustainable technologies (biomass upgrading, water purification, CO2 capture)- Updated references for advanced readers The is an essential reference for chemical engineers, scientists in the manufacturing and sustainability industry and post-graduate scholars working on MOFs and chemical catalysis.

Recent Trends and the Future of Antimicrobial Agents provides a significantly expanded overview of the topic with updated research in a broader context on the development of alternative approaches against microbial infections. This part consists of ten chapters. The first five chapters describe naturally derived antimicrobial compounds such as plant-based antimicrobials (PBAs), enzymes based and antibody-based antibacterial therapeutic and secondary metabolites from plant endophytes. The book proceeds to provide details aboutantimicrobials derived from marine microorganisms (bacteria, fungi, actinomycetes, and cyanobacteria) is included to inform readers about effective medications against MDR strains. Specific chapters describe the drug development against protozoans, with one chapter focusing on Plasmodium. Chapter contributors have postulated novel approaches for antimalarial therapeutics. The book also includes an explanation of host target identification and drug discovery with the purpose of informing the reader about the implications in viral biology and how they could be exploited for treating viral diseases. The contents cater to the information needs of professionals and learners in academia, industry and health services who aim to learn the most significant experimental and practical approaches towards finding alternatives to existing antimicrobial therapies.