📗 Libro en inglés PAIN, THE OPIOID EPIDEMIC, AND DEPRESSION

Long term prescription opioid use occurs in a substantial proportion of new opioid users Most concerning is that high risk patients with comorbid depression anxiety nicotine dependence and substance use disorders compared to patients without these factors continue to be prescribed higher opioid doses for longer durations and are more likely to receive opioids with high abuse potential To understand this phenomenon we must consider the relationships between pain mental illness substance use disorder and long term prescription opioid use While separate fields have investigated the bi directional relationships between depression pain and long term prescription opioid use independently of one another there is no text which has brought together the complex interaction of all three together Drawing on contributions from neuroscience pain psychiatry clinical epidemiology pharmacoepidemiology clinical trials and research on social determinants of health Pain the Opioid Epidemic and Depression is the first book to integrate currently siloed areas of investigation and clinical knowledge This book takes a comprehensive approach from neurophysiology to epidemiology to clinical practice and explains the processes driving maintenance of chronic pain persis